Endocrine Abstracts

IntroductionRadioactive iodine (RAI) is a well-established treatment for relapsed Graves and toxic nodular hyperthyroidism. Lithium reduces the release of organic iodide and thyroid hormones from the thyroid gland, which results in a reduction of urinary radioiodine excretion. Previous studies have shown lithium may improve the effectiveness of radioiodine therapy; however research in this area is limited.Objective<p class="abs...

Background: Radioiodine (RAI) is highly effective in the treatment of hyperthyroidism. Lithium reduces thyroidal release of organic iodide and thyroid hormones, thus increasing thyroid retention of RAI and subsequently, the delivered dose of radiation. Controversy surrounds whether lithium increases the efficacy of RAI.Aims: To assess whether lithium improved outcome after radioiodine treatment and analyse fT4 and eye disease changes in lithium treatment...

Background: Close follow up of patients treated with radioiodine (RAI) for hyperthyroidism is imperative to ensure that resultant hypothyroidism or ensuing hyperthyroidism is detected promptly and treated. Protocols of follow up vary between hospitals. In our centre, a telephone clinic is used and patients are called after thyroid function tests at 1, 3, 6, 9 and 12 weeks post radioiodine.Aims: To audit patient follow up in the telephone clinic, comparin...

IntroductionPatients treated with radioiodine (RAI) for thyrotoxicosis, secondary to Graves or a toxic nodule, require close follow up to determine whether they have become hypothyroid or have a recurrence. National guidelines state that patients should have their first blood test at about six weeks post RAI. Telephoning patients with their results, rather than reviewing them at outpatient appointments, can be a more convenient and efficient method of fo...

Introduction: Radioactive Iodine (RAI) is a well-established and effective treatment for hyperthyroidism. Lithium (Li) blocks the release of organic iodide and thyroid hormone from the thyroid gland without effecting thyroidal RAI uptake. Through decreasing the loss of RAI from the thyroid it has also been shown to reduce urinary RAI excretion. Its use as an adjunct to RAI in the therapy of hyperthyroidism has been postulated, but information on the subject is limited.<p c...